The Effects of Menopause on Joint Pain and Bone Health: Understanding the Changes London Bridge Orthopaedics At some point in midlife, you might notice that sex is different. Shifts in hormones can affect everything from desire to natural lubrication, which means arousal doesn't always come as easily as Interactions Between Inflammation and Female Sexual Desire and Arousal Function Current Sexual Health Reports Springer Nature Link Hormones and their functions in the human body Male vs Female Hormonal Cycle Hormones are chemical messengers in your body. For males, the main hormone is testosterone, produced in the testicles. It's responsible for male characteristics, sperm production, and sex Understanding sexual arousal and subjectivegenital arousal desynchrony in women Nature Reviews Urology